Angiotensin II receptor antagonist

Antagonists of angiotensin II receptors, or blockers of AT1 receptors is one of the new groups of antihypertensive drugs. It unites drugs that modulate the functioning of the renin-angiotensin-aldosterone system (RAAS) through interaction with angiotensin receptors.

The RAAS plays an important role in regulating blood pressure, the pathogenesis of hypertension and chronic heart failure (CHF), as well as a number of other diseases. The angiotensin (angio — vascular and tensio — a strain) — peptides produced in the body from angiotenzinoguena, which is a glycoprotein (ALPHA2-globulin) in blood plasma, which is synthesized in the liver. Under the influence of renin (an enzyme produced in juxtaglomerular apparatus of the kidney) polypeptide angiotensinogen non-Pressor activity, hydrolyses, forming angiotensin I is a biologically inactive Decapeptide, who are easily exposed to the further transformations. Under the action of angiotensin converting enzyme (ACE) produced in lungs, angiotensin I is converted into the octapeptide — angiotensin II, a highly active endogenous pressory connection.

Angiotensin II is the main effector peptide of the RAAS. He has a strong vasoconstrictor effect, increases in systemic vascular resistance, causes a rapid increase in blood pressure. In addition, it stimulates secretion of aldosterone, and in large concentrations — increases secretion of antidiuretic hormone (increased reabsorption of sodium and water, hypervolemia) and causes sympathetic activation. All of these effects contribute to the development of hypertension.



Angiakand (Candesartan)

Angiakand (Candesartan)

Expiration date: 02/2019 Dosage form: tabletsComposition:Dosage 8 mg1 tablet contains: act..

$6.81

Aprovasc (Amlodipine + Irbesartan)

Aprovasc (Amlodipine + Irbesartan)

Expiration date: 01/2020 Release form, composition and packagingTablets, film-coated white colo..

$21.42

Aprovel (Irbesartan)

Aprovel (Irbesartan)

Expiration date: 05/2020 The composition and form of issue:Tablets. 1 tablet contains irbesarta..

$10.71

Atacand (Candesartan)

Atacand (Candesartan)

Expiration date: 09/2019 The composition and form of issue:Tablets. 1 tablet contains:active su..

$58.41

Atacand Plus (Hydrochlorothiazide + Candesartan) 16mg + 12.5mg 28 tablets

Atacand Plus (Hydrochlorothiazide + Candesartan) 16mg + 12.5mg 28 tablets

Expiration date: 09/2019 The composition and form of issue:Tablets. 1 tablet contains active su..

$58.41

Bloctran (Losartan)

Bloctran (Losartan)

Expiration date: 05/2020 Release form and composition:Tablets, film-coated light pink-orange, r..

$6.81

Bloctran GT (Losartan + Hydrochlorothiazide) 12.5mg + 50mg 30 tablets

Bloctran GT (Losartan + Hydrochlorothiazide) 12.5mg + 50mg 30 tablets

Expiration date: 10/2018 Composition:Active ingredients: losartan potassium, hydrochlorothiazid..

$9.74

Candesartan

Candesartan

Expiration date: 08/2019 Action: Hypotensive Composition: Candesartan 16 or 32 m..

$7.79

Cardosal (Olmesartan medoxomil)

Cardosal (Olmesartan medoxomil)

Expiration date: 02/2020 Clinico-pharmacological group(Antagonist of angiotensin II receptor)Re..

$14.60

Cardosal Plus (Hydrochlorothiazide + Olmesartan medoxomil) 12.5mg + 20mg 28 tablets

Cardosal Plus (Hydrochlorothiazide + Olmesartan medoxomil) 12.5mg + 20mg 28 tablets

Expiration date: 12/2021 Action:hypotensivereduction of blood pressure during 24hCompositi..

$19.47

Co-Diovan (Valsartan + Hydrochlorothiazide)

Co-Diovan (Valsartan + Hydrochlorothiazide)

Expiration date: 02/2020 The composition and form of issue:Tablets, film-coated. 1 tablet conta..

$54.52

Co-Exforge (Amlodipine + Valsartan + Hydrochlorothiazide)

Co-Exforge (Amlodipine + Valsartan + Hydrochlorothiazide)

Expiration date: 01/2019 The composition and form of issue:Tablets, film-coated. 1 tablet conta..

$70.09

Cozaar (Losartan)

Cozaar (Losartan)

Expiration date: 06/2020 The composition and form of issue:1 tablet contains losartan potassium..

$9.74

Diovan (Valsartan)

Diovan (Valsartan)

Expiration date: 02/2020 The composition and form of issue:Tablets, film-coated. 1 tablet ..

$38.94

Duopress (Valsartan + Hydrochlorothiazide)

Duopress (Valsartan + Hydrochlorothiazide)

Expiration date: 06/2020 Composition1 tablet contains active substance: valsartan - 80,0 mg and..

$7.79

Edarbi (Azilsartan medoxomil)

Edarbi (Azilsartan medoxomil)

Expiration date: 02/2020 Action: angiotensin ll receptor antagonist Composition:..

$13.63

Exforge (Amlodipine + Valsartan)

Exforge (Amlodipine + Valsartan)

Expiration date: 03/2020 The composition and form of issue:Tablets, film-coated. 1 tablet conta..

$48.68

Hyposart (Candesartan)

Hyposart (Candesartan)

Expiration date: 07/2019 Action:AntihypertensiveComposition:Candesartan 8, 16 or 32 mgAccesso.o..

$7.79

Hyzaar (Losartan + Hydrochlorothiazide) 50mg + 12.5mg 14 tablets

Hyzaar (Losartan + Hydrochlorothiazide) 50mg + 12.5mg 14 tablets

Expiration date: 11/2019 The composition and form of issue:1 tablet coated liner contains ..

$13.63

Hyzaar forte (Losartan + Hydrochlorothiazide) 100mg + 12.5mg 28 tablets

Hyzaar forte (Losartan + Hydrochlorothiazide) 100mg + 12.5mg 28 tablets

Expiration date: 01/2020 The composition and form of issue:Tablets, film-coated. 1 tablet conta..

$27.26

Irsar (Irbesartan)

Irsar (Irbesartan)

Expiration date: 04/2018 Action:Lowering blood pressureComposition:Irbesartan-150mgAccesso.othe..

$10.51

Ksarten (Candesartan)

Ksarten (Candesartan)

Expiration date: 03/2018 Action: AntihypertensiveComposition:Candesartan, door accessory, ..

$12.66

Lorista (Losartan)

Lorista (Losartan)

Expiration date: 04/2022 The composition and form of issue:Tablets, film-coated. 1 tablet conta..

$5.84

Lorista H (Hydrochlorothiazide + Losartan)

Lorista H (Hydrochlorothiazide + Losartan)

Expiration date: 11/2021 The composition and form of issue:Tablets, film-coated 1 tablet contai..

$7.79

Lorista H 100 (Hydrochlorothiazide + Losartan)

Lorista H 100 (Hydrochlorothiazide + Losartan)

Expiration date: 30 tablets - 05/2020 90 tablets - 06/2022 Action: Antihypertens..

$9.74

Lorista HD (Hydrochlorothiazide + Losartan)

Lorista HD (Hydrochlorothiazide + Losartan)

Expiration date: 02/2022 The composition and form of issue:Tablets, film-coated 1 tablet contai..

$11.68

Lortenza (Amlodipine + Losartan)

Lortenza (Amlodipine + Losartan)

Expiration date: 04/2019 Action:Antihypertensive agentsComposition:Amlodipine - 5 or 10 mg, los..

$8.76

Losarel (Losartan) 5mg 30 tablets

Losarel (Losartan) 5mg 30 tablets

Expiration date: 05/2019 The composition and form of issue:Tablets, film-coated 1 tablet contai..

$7.79

Losartan H (Hydrochlorothiazide + Losartan) Kanon

Losartan H (Hydrochlorothiazide + Losartan) Kanon

Expiration date: 06/2019 CompositionDosage of 12.5 mg + 50 mg1 tablet, film-coated, contains:ac..

$5.84

Losartan H (Hydrochlorothiazide + Losartan) Richter

Losartan H (Hydrochlorothiazide + Losartan) Richter

Expiration date: 09/2020 Action: hypotensive Composition: losartan potassium 50 ..

$8.76

Losartan Kanon

Losartan Kanon

Expiration date: 06/2019 Pharmacological action : Antihypertensive.Blocks the angiotensin ..

$5.84

Losartan Ozon

Losartan Ozon

Expiration date: 08/2020 Composition1 tablet contains: losartan potassium 12.5 mg, 50 mg or 100..

$4.87

Losartan Richter

Losartan Richter

Expiration date: 08/2021 Action: hypotensive Composition: Losartan 50 or 100 mg&..

$6.62

Losartan Teva

Losartan Teva

Expiration date: 01/2020 Release form Pills Packaging 30 PCs Pharmacologica..

$6.81

Losartan Vertex

Losartan Vertex

Expiration date: 03/2021 Action:Antihypertensive agentsComposition:losartan potassium 25, 50 or..

$5.84

Lozap (Losartan)

Lozap (Losartan)

Expiration date: 04/2020 Composition 1 tablet, film-coated, contains: 12.5, 50 or 100 mg o..

$5.84

Micardis Plus (Hydrochlorothiazide + Telmisartan) 80mg/12.5mg 28 tablets

Micardis Plus (Hydrochlorothiazide + Telmisartan) 80mg/12.5mg 28 tablets

Expiration date: 07/2019 The composition and form of issue: Tablets. 1 tablet contains act..

$27.26

Nortivan (Valsartan)

Nortivan (Valsartan)

Expiration date: 09/2019 The composition and form of issue:Tablets, film-coated 1 tablet contai..

$7.79

Ordiss (Candesartan)

Ordiss (Candesartan)

Expiration date: 06/2019 Composition:1 tablet contains:active substance: candesartan in ts..

$11.68

Ordiss H (Hydrochlorothiazide + Candesartan) 16mg + 12.5mg 30 tablets

Ordiss H (Hydrochlorothiazide + Candesartan) 16mg + 12.5mg 30 tablets

Expiration date: 01/2019 Release form, composition Pills Ardyss N lenticular, capsulo..

$13.63

Presartan (Losartan)

Presartan (Losartan)

Expiration date: 04/2020 Release form and composition: Tablets, film-coated pink, round, l..

$5.84

Telmista (Telmisartan)

Telmista (Telmisartan)

Expiration date: 04/2020 ..

$9.74

Telsap (Telmisartan)

Telsap (Telmisartan)

Expiration date: 03/2019 ..

$9.74

Teveten (Eprosartan)

Teveten (Eprosartan)

Expiration date: 11/2019 The composition and form of issue: Tablets, film-coated 1 tablet ..

$33.10

Teveten Plus (Hydrochlorothiazide + Eprosartan)

Teveten Plus (Hydrochlorothiazide + Eprosartan)

Expiration date: 11/2019 The composition and form of issue: Tablets, film-coated. 1 t..

$33.10

Twynsta (Amlodipine + Telmisartan)

Twynsta (Amlodipine + Telmisartan)

Expiration date: 11/2019 Feature: release form, composition Tablet Twynsta oval, bico..

$31.15

Valsacor (Valsartan)

Valsacor (Valsartan)

Expiration date: 08/2022 Description pharmaceutical form: Tablets 80 mg: round, biconvex t..

$8.76

Valsacor H (Valsartan + Hydrochlorothiazide)

Valsacor H (Valsartan + Hydrochlorothiazide)

Expiration date: 03/2020 Action: antihypertensive effect, diuretic Composition:V..

$7.79

Valsacor HD (Valsartan + Hydrochlorothiazide)

Valsacor HD (Valsartan + Hydrochlorothiazide)

Expiration date: 01/2021 Action: antihypertensive effect, diuretic Composition:Valsar..

$9.74

Valsartan

Valsartan

Expiration date: 08/2020 Composition Active substance: valsartan - 40,0 mg, 80,0 160,..

$5.84

Valsartan Zentiva

Valsartan Zentiva

Expiration date: 05/2019 Action: hypotensive effect Composition:Valsartan 80 and..

$7.79

Valz (Valsartan)

Valz (Valsartan)

Expiration date: 01/2020 Dosage form Oval biconvex tablets, film-coated brown colour, scor..

$8.76

Vamloset (Amlodipine + Valsartan)

Vamloset (Amlodipine + Valsartan)

Expiration date: 08/2020 Action: antianginal and hypotensive action Composition:amlod..

$7.79

Vasotens (Losartan)

Vasotens (Losartan)

Expiration date: 03/2019 Action: The hypotensive Composition: losartan potassium..

$5.84

Vasotens H (Losartan + Hydrochlorothiazide)

Vasotens H (Losartan + Hydrochlorothiazide)

Expiration date: 02/2019 Release form, composition Tablets, film-coated white color, round..

$9.74

Micardis (Telmisartan)

Micardis (Telmisartan)

Expiration date: 10/2020 Active substance: Telmisartan. The drug forms Tablets 4..

$17.52

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