Serotonergic

This group includes drugs that interact with specific serotonin or 5-HT (5-hydroxytryptamine) receptors. Serotonin contains almost all organs and tissues, however, more than 90% found in enterochromaffin cells of the gastrointestinal tract. Blood accumulates serotonin (active transport) in platelets, in the Central nervous system in serotonergic neurons; the latter it is synthesized and released.

Pharmacological effects of serotonin are mediated by the excitation of 5-HT1, 5-HT2 and 5-HT3-type serotonin receptors. Its main effect is the contraction of smooth muscle, vasoconstriction (except of vessels in skeletal muscle and heart), increased blood pressure, activation of platelet aggregation, increased tone and peristalsis of the gastrointestinal tract, stimulation of pain and the development of nausea and vomiting. Some serotonergic agents (serotonin, Maximin, etc.) stimulate serotonin receptors and are used primarily in hemorrhagic syndrome, Hypo - and aplastic anemia, hemorrhagic vasculitis, others — digidrirovannye ergot alkaloids (dihydroergotamine), some antihistamines and antiemetics block the 5-HT receptors, relieve peripheral vasoconstriction and Pressor effects of serotonin, suppress the gag reflex and allergies; these latter have found wide use as tools for the treatment of migraine and headache (sumatriptan, etc.), nausea and vomiting (ondansetron, tropisetron, granisetron, etc.), hypertension.



Amigrenin (Sumatriptan)

Amigrenin (Sumatriptan)

Expiration date: 01/2021 The composition and form of issue: Tablets, film-coated. 1 tablet..

$7.08

Emetron (Ondansetron)

Emetron (Ondansetron)

Expiration date: 11/2020 The composition and form of issue: Solution for injection 1 ..

$21.24

Imigran (Sumatriptan)

Imigran (Sumatriptan)

Expiration date: 02/2020 The composition and form of issue: Tablets, film-coated. 1 tablet..

$8.85

Latran (Ondansetron) 4mg 10 tablets

Latran (Ondansetron) 4mg 10 tablets

Expiration date: 02/2020 The composition and form of issue: Solution for intravenous and i..

$14.16

Mygrepam (Zolmitriptan) 2.5mg 2 tablets

Mygrepam (Zolmitriptan) 2.5mg 2 tablets

Expiration date: 04/2020 Mygrepam® effectively relieves headache and other symptoms of migraine..

$7.08

Ondansetron 16mg 2 suppositories

Ondansetron 16mg 2 suppositories

Expiration date: 01/2019 Release form and composition: Rectal suppositories white or white..

$18.58

Ondansetron 2mg/ml 2ml 5 vials

Ondansetron 2mg/ml 2ml 5 vials

Expiration date: 08/2018 Composition1 ampoule contains ondansetron (in the form of hydrochlorid..

$8.32

Ondansetron 2mg/ml 4ml 5 vials

Ondansetron 2mg/ml 4ml 5 vials

Expiration date: 09/2019 The composition and form of issue Ondansetron solution for in/in ..

$9.82

Ondansetron 8mg 10 tablets

Ondansetron 8mg 10 tablets

Expiration date: 02/2020 Group affiliation: Anti-emetic - serotonin antagonistDescription ..

$10.62

Rapimed (Sumatriptan) 100mg 6 tablets

Rapimed (Sumatriptan) 100mg 6 tablets

Expiration date: 08/2019 Clinico-pharmacological group (Agonist of serotonin 5-HT1-recepto..

$22.57

Relpax (Eletriptan) 40mg 2 tablets

Relpax (Eletriptan) 40mg 2 tablets

Expiration date: 10/2018. Structure and Composition: Tablets, film-coated. 1 tablet c..

$14.16

Resolor (Prucalopride)

Resolor (Prucalopride)

Expiration date: 10/2019 Action: enhances intestinal motilityComposition:Prucalopride 1 or..

$47.79

Sumamigren (Sumatriptan)

Sumamigren (Sumatriptan)

Expiration date: 02/2021 Action: Anti-migraine remedyComposition:Sumatriptan 50 or 100 mgO..

$8.85

Sumatriptan

Sumatriptan

Expiration date: 11/2019 Compositionsumatriptan 50 or 100 mgexcipients: hyprolose (GI the gorse..

$5.31

Sumatriptan 50mg 2 tablets

Sumatriptan 50mg 2 tablets

Expiration date: 10/2019 Action: Anti migraineComposition:sumatriptan 50mgAuxiliary substa..

$4.42

Sumatriptan OBL

Sumatriptan OBL

Expiration date: 01/2019 Action: specific selective agonist of 5-HT1-serotonin receptors l..

$3.89

Sumatriptan Teva 100mg 2 tablets

Sumatriptan Teva 100mg 2 tablets

Expiration date: 10/2019 Action: Anti migraineComposition:sumatriptan 100mgAuxiliary subst..

$9.73

Sumatriptan Vertex

Sumatriptan Vertex

Expiration date: 11/2019 Action: Anti migraineComposition:sumatriptan 50 or 100mgAuxiliary..

$5.31

Vegaprat (Prucalopridum)

Vegaprat (Prucalopridum)

Expiration date: 02/2018 Active substance: Prucalopride * (Prucalopridum)Pharmacological groups..

$22.12

Zofran (Ondansetron)

Zofran (Ondansetron)

Expiration date: 05/2019 The composition and form of issue: Solution for intravenous and i..

$21.24

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