• Phenzitat (phenazepam)

Expiration date: 05/2019 


1 tablet contains 0.5 or 1 mg Bromdihydrochlorphenylbenzodiazepine 


50 pcs.

pharmachologic effect

Phenzitat has anxiolytic, anticonvulsant, muscle relaxant, central, hypnotic, sedative to applicable. Stimulates the benzodiazepine receptors, it increases the sensitivity of GABA receptors to mediator, increases the braking effect of GABA in the CNS. Reduces the excitability of the subcortical brain structures inhibits polisinapticheskie spinal reflexes. It reduces emotional stress, reduces anxiety, fear, anxiety. It suppresses the spread of excitation arising in the epileptogenic foci in the cortex, the thalamus, and limbic structures of the brain by increasing presynaptic inhibition (increased focus activity is not reduced).


Neurotic, neurosis, psychopathic and psychopathic state, accompanied by anxiety, fear, increased irritability, tension and emotional lability, sleep disorders, obsessive-compulsive disorder, panic disorder, phobias, reactive psychosis, autonomic lability, hypochondriacally-senestopatichesky syndrome, seizures of various etiologies, temporal and myoclonic epilepsy, status epilepticus, muscle rigidity, teak, athetosis, hyperkinesia, premedication (as a component of induction of anesthesia), in the complex therapy of opioid and for abuse syndrome, schizophrenia (febrile form, increased sensitivity to antipsychotics), prevention of states of fear and emotional stress.


Severe myasthenia gravis, severe liver damage (cirrhosis, Botkin's disease) and kidney poisoning others. Tranquilizers, antipsychotics, hypnotics, narcotics, alcohol, pregnancy, breast-feeding.

Pregnancy and breast-feeding

Contraindicated during pregnancy. At the time of treatment should stop breastfeeding.

Dosing and Administration

Phenzitat taken orally. The mode set is strictly individual, depending on the indications of the disease, tolerance and others.

When administered a single dose for adults is usually 0.5-1 mg (with sleep disorders - 0.25-0.5 mg), the average daily - 1.5-5 mg 2-3 hours (typically 0.5 -1 mg in the morning and during the day and 2.5 mg at night), the maximum daily - 10 mg.

Neurotic, neurosis, psychopathic and psychopathic states: Inside, the initial dose of 0.5-1 mg 2-3 times a day, 2-3 days (if necessary) - up to 4-6 mg / day, in severe agitation initial dose - 3 mg / day, then rapidly increasing the dose until a therapeutic effect.

Neurological Practice (disease with increased muscle tone), inside of 2-3 mg 1-2 times a day or in / m, 0.5 mg 1-2 times a day.

Status epilepticus, serial seizures: in / m or / in, starting with a dose of 0.5 mg. In the treatment of epilepsy - 2.10 mg / day.

Alcohol withdrawal: inside, 2.5-5 mg / day.

Side effects

From the nervous system and sensory organs: dizziness, headache, drowsiness, muscle weakness, impaired memory, concentration, coordination, paradoxical excitement, ataxia, mydriasis.

From the digestive tract: dry mouth, nausea, diarrhea.

Allergic reactions: skin rash, pruritus.

Other: dysuria, dysmenorrhea, loss of libido, addiction, drug dependency.

special instructions

As an equalizer avoids or reduces some of the side effects that can be applied mesocarb. Be wary of the organic cerebral insufficiency. The lifting should be done gradually by reducing the dose to reduce the risk of withdrawal symptoms.

Should not be used during the drivers of vehicles and people skills relate to the high concentration of attention. At the time of treatment should abandon admission alcohol.

Drug interactions

(Mutually) effect of neuroleptics, tranquilizers, sleeping pills, narcotic, analgesic, anticonvulsant drugs, and alcohol.


Symptoms: marked depression of consciousness, cardiac and respiratory activity.

Treatment: control of vital functions, maintaining respiratory and cardiovascular activity, symptomatic therapy. Specific antagonist flumazenil (w / 0.2 mg - optionally up to 1 mg - 5% glucose solution or 0.9% sodium chloride solution).

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Phenzitat (phenazepam)

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